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Dabigatran abrogates brain endothelial cell permeability in response to thrombin

Atrial fibrillation (AF) increases the risk and severity of thromboembolic stroke. Generally, antithrombotic agents increase the hemorrhagic risk of thromboembolic stroke. However, significant reductions in thromboembolism and intracerebral hemorrhage have been shown with the antithrombin dabigatran...

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Bibliografiska uppgifter
I publikationen:J Cereb Blood Flow Metab
Huvudupphovsmän: Hawkins, Brian Thomas, Gu, Yu-Huan, Izawa, Yoshikane, del Zoppo, Gregory John
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640263/
https://ncbi.nlm.nih.gov/pubmed/25669912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.9
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