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Dabigatran abrogates brain endothelial cell permeability in response to thrombin

Atrial fibrillation (AF) increases the risk and severity of thromboembolic stroke. Generally, antithrombotic agents increase the hemorrhagic risk of thromboembolic stroke. However, significant reductions in thromboembolism and intracerebral hemorrhage have been shown with the antithrombin dabigatran...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Hawkins, Brian Thomas, Gu, Yu-Huan, Izawa, Yoshikane, del Zoppo, Gregory John
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640263/
https://ncbi.nlm.nih.gov/pubmed/25669912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.9
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