Bayesian modeling suggests that IL-12 (p40), IL-13 and MCP-1 drive murine cytokine networks in vivo

BACKGROUND: Cytokine-hormone network deregulations underpin pathologies ranging from autoimmune disorders to cancer, but our understanding of these networks in physiological/pathophysiological states remains patchy. We employed Bayesian networks to analyze cytokine-hormone interactions in vivo using...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Field, Sarah L., Dasgupta, Tathagata, Cummings, Michele, Savage, Richard S., Adebayo, Julius, McSara, Hema, Gunawardena, Jeremy, Orsi, Nicolas M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640223/
https://ncbi.nlm.nih.gov/pubmed/26553024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0226-3
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