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Variant mapping and mutation discovery in inbred mice using next-generation sequencing
BACKGROUND: The development of powerful new methods for DNA sequencing enable the discovery of sequence variants, their utilization for the mapping of mutant loci, and the identification of causal variants in a single step. We have applied this approach for the analysis of ENU-mutagenized mice maint...
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| Publicado no: | BMC Genomics |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640199/ https://ncbi.nlm.nih.gov/pubmed/26552429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2173-1 |
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