Variant mapping and mutation discovery in inbred mice using next-generation sequencing

BACKGROUND: The development of powerful new methods for DNA sequencing enable the discovery of sequence variants, their utilization for the mapping of mutant loci, and the identification of causal variants in a single step. We have applied this approach for the analysis of ENU-mutagenized mice maint...

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Sparad:
Bibliografiska uppgifter
I publikationen:BMC Genomics
Huvudupphovsmän: Gallego-Llamas, Jabier, Timms, Andrew E., Geister, Krista A., Lindsay, Anna, Beier, David R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Methodology Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640199/
https://ncbi.nlm.nih.gov/pubmed/26552429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2173-1
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