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Enhancement of Solubility of Lamotrigine by Solid Dispersion and Development of Orally Disintegrating Tablets Using 3(2) Full Factorial Design

Present investigation deals with the preparation and evaluation of orally disintegrating tablets (ODTs) of lamotrigine using β-cyclodextrin and PVP-K30 as polymers for the preparation of solid dispersion which help in enhancement of aqueous solubility of this BCS CLASS-II drug and sodium starch glyc...

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Detalhes bibliográficos
Publicado no:J Pharm (Cairo)
Main Authors: Singh, Jatinderpal, Garg, Rajeev, Gupta, Ghanshyam Das
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639876/
https://ncbi.nlm.nih.gov/pubmed/26634173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/828453
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