Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy

Proliferative vitreoretinopathy (PVR) is a serious complication of retinal detachment and ocular trauma, and its recurrence may lead to irreversible vision loss. Epithelial to mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a critical step in the pathogenesis of PVR, which...

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Udgivet i:Sci Rep
Main Authors: Ishikawa, Keijiro, He, Shikun, Terasaki, Hiroto, Nazari, Hossein, Zhang, Huiming, Spee, Christine, Kannan, Ram, Hinton, David R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639835/
https://ncbi.nlm.nih.gov/pubmed/26552368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16386
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