A Holistic Multi Evidence Approach to Study the Fragmentation Behaviour of Crystalline Mannitol

Mannitol is an essential excipient employed in orally disintegrating tablets due to its high palatability. However its fundamental disadvantage is its fragmentation during direct compression, producing mechanically weak tablets. The primary aim of this study was to assess the fracture behaviour of c...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Koner, Jasdip S., Rajabi-Siahboomi, Ali, Bowen, James, Perrie, Yvonne, Kirby, Daniel, Mohammed, Afzal R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639810/
https://ncbi.nlm.nih.gov/pubmed/26553127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16352
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