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A Holistic Multi Evidence Approach to Study the Fragmentation Behaviour of Crystalline Mannitol
Mannitol is an essential excipient employed in orally disintegrating tablets due to its high palatability. However its fundamental disadvantage is its fragmentation during direct compression, producing mechanically weak tablets. The primary aim of this study was to assess the fracture behaviour of c...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4639810/ https://ncbi.nlm.nih.gov/pubmed/26553127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16352 |
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