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Assembly of cartilage collagen fibrils is disrupted by overexpression of normal type II collagen in transgenic mice.

Cartilage collagen fibrils, which are characterized by their thin, uniform diameters, are formed of a multicomponent system of three collagen types (II, IX, and XI) and interacting proteoglycans. We have used a genetic approach to test whether the proper assembly of this multiprotein structure was a...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Garofalo, S, Metsäranta, M, Ellard, J, Smith, C, Horton, W, Vuorio, E, de Crombrugghe, B
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46398/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8483900/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.3825
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