Assembly of cartilage collagen fibrils is disrupted by overexpression of normal type II collagen in transgenic mice.

Cartilage collagen fibrils, which are characterized by their thin, uniform diameters, are formed of a multicomponent system of three collagen types (II, IX, and XI) and interacting proteoglycans. We have used a genetic approach to test whether the proper assembly of this multiprotein structure was a...

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Hauptverfasser: Garofalo, S, Metsäranta, M, Ellard, J, Smith, C, Horton, W, Vuorio, E, de Crombrugghe, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC46398/
https://ncbi.nlm.nih.gov/pubmed/8483900
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