REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation

The role of REST changes in neurons, including the rapid decrease of its level during differentiation and its fluctuations during many mature functions and diseases, is well established. However, identification of many thousand possible REST-target genes, mostly based on indirect criteria, and demon...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Garcia-Manteiga, Jose M., Bonfiglio, Silvia, Folladori, Lucrezia, Malosio, Maria L., Lazarevic, Dejan, Stupka, Elia, Cittaro, Davide, Meldolesi, Jacopo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639699/
https://ncbi.nlm.nih.gov/pubmed/26617488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00438
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