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REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation

The role of REST changes in neurons, including the rapid decrease of its level during differentiation and its fluctuations during many mature functions and diseases, is well established. However, identification of many thousand possible REST-target genes, mostly based on indirect criteria, and demon...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Garcia-Manteiga, Jose M., Bonfiglio, Silvia, Folladori, Lucrezia, Malosio, Maria L., Lazarevic, Dejan, Stupka, Elia, Cittaro, Davide, Meldolesi, Jacopo
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639699/
https://ncbi.nlm.nih.gov/pubmed/26617488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00438
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