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The Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor Environment

The membrane protein low-density lipoprotein receptor related-protein 1 (LRP1) has been attributed a role in cancer. However, its presumably often indirect involvement is far from understood. LRP1 has both endocytic and signaling activities. As a matricellular receptor it is involved in regulation,...

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Опубликовано в: :Front Pharmacol
Главные авторы: Van Gool, Bart, Dedieu, Stéphane, Emonard, Hervé, Roebroek, Anton J. M.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639618/
https://ncbi.nlm.nih.gov/pubmed/26617523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00271
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