Cellular Cholesterol Distribution Influences Proteolytic Release of the LRP-1 Ectodomain

Low-density lipoprotein receptor-related protein-1 (LRP-1) is a multifunctional matricellular receptor composed of a large ligand-binding subunit (515-kDa α-chain) associated with a short trans-membrane subunit (85-kDa β-chain). LRP-1, which exhibits both endocytosis and cell signaling properties, p...

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Vydáno v:Front Pharmacol
Hlavní autoři: Dekky, Bassil, Wahart, Amandine, Sartelet, Hervé, Féré, Michaël, Angiboust, Jean-François, Dedieu, Stéphane, Piot, Olivier, Devy, Jérôme, Emonard, Hervé
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751253/
https://ncbi.nlm.nih.gov/pubmed/26903870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00025
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