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Adaptive Design of Confirmatory Trials: Advances and Challenges

The past decade witnessed major developments in innovative designs of confirmatory clinical trials, and adaptive designs represent the most active area of these developments. We give an overview of the developments and associated statistical methods in several classes of adaptive designs of confirma...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials
Main Authors: Lai, Tze Leung, Lavori, Philip W., Tsang, Ka Wai
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639447/
https://ncbi.nlm.nih.gov/pubmed/26079372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2015.06.007
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