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Anti-emetic drug maropitant induces intestinal motility disorder but not anti-inflammatory action in mice
Maropitant is a neurokinin 1 receptor (NK1R) antagonist that is clinically used as a new anti-emetic drug for dogs. Substance P (SP) and its receptor NK1R are considered to modulate gastrointestinal peristalsis. In addition, SP works as an inflammatory mediator in gastrointestinal diseases. Aim of t...
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| Publicado no: | J Vet Med Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Japanese Society of Veterinary Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4638283/ https://ncbi.nlm.nih.gov/pubmed/25947563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.15-0182 |
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