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Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

The blood-brain barrier (BBB) maintains brain homeostasis by limiting entry of substances to the central nervous system through interaction of transmembrane and intracellular proteins that make up endothelial cell tight junctions (TJs). Recently it was shown that the BBB can be modulated by disease...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Brooks, Tracy A., Hawkins, Brian T., Huber, Jason D., Egleton, Richard D., Davis, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638185/
https://ncbi.nlm.nih.gov/pubmed/15792985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01288.2004
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