Histone methylation levels correlate with TGFBIp and extracellular matrix gene expression in normal and granular corneal dystrophy type 2 corneal fibroblasts

BACKGROUND: TGFβ1-induced expression of transforming growth factor β-induced protein (TGFBIp) and extracellular matrix (ECM) genes plays a major role in the development of granular corneal dystrophy type 2 (GCD2: also called Avellino corneal dystrophy). Although some key transcription factors are kn...

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Gepubliceerd in:BMC Med Genomics
Hoofdauteurs: Maeng, Yong-Sun, Lee, Ga-Hyun, Choi, Seung-Il, Kim, Kyu Seo, Kim, Eung Kweon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638082/
https://ncbi.nlm.nih.gov/pubmed/26553048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0151-8
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