Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation

The protein substrates of sirtuin 5-regulated lysine malonylation (Kmal) remain unknown, hindering its functional analysis. In this study, we carried out proteomic screening, which identified 4042 Kmal sites on 1426 proteins in mouse liver and 4943 Kmal sites on 1822 proteins in human fibroblasts. I...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Principais autores: Colak, Gozde, Pougovkina, Olga, Dai, Lunzhi, Tan, Minjia, te Brinke, Heleen, Huang, He, Cheng, Zhongyi, Park, Jeongsoon, Wan, Xuelian, Liu, Xiaojing, Yue, Wyatt W., Wanders, Ronald J. A., Locasale, Jason W., Lombard, David B., de Boer, Vincent C. J., Zhao, Yingming
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638046/
https://ncbi.nlm.nih.gov/pubmed/26320211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.048850
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados