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The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior

In response to diverse stresses, the tumor suppressor p53 differentially regulates its target genes, variably inducing cell cycle arrest, apoptosis or senescence. Emerging evidence indicates that p53 plays an important role in regulating hematopoietic stem cell (HSC) quiescence, self-renewal, apopto...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Liu, Yan, Elf, Shannon E., Asai, Takashi, Miyata, Yasuhiko, Liu, Yuhui, Sashida, Goro, Huang, Gang, Giandomenico, Silvana Di, Koff, Andrew, Nimer, Stephen D.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637974/
https://ncbi.nlm.nih.gov/pubmed/19755852
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