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Demethylation of miR-10b plays a suppressive role in ccRCC cells

MicroRNAs have been implicated in cancer cells proliferation, migration and invasion, including clear-cell renal cell carcinoma (ccRCC). DNA methylation, a major epigenetic change associated with cancer, may lead to transcriptional silencing of tumor suppressor genes, including miRNAs, which may be...

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Bibliografische gegevens
Gepubliceerd in:Int J Clin Exp Pathol
Hoofdauteurs: He, Cheng, Zhao, Xiaokun, Jiang, Hongyi, Zhong, Zhaohui, Xu, Ran
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637584/
https://ncbi.nlm.nih.gov/pubmed/26617769
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