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ERK5 negatively regulates tobacco smoke-induced pulmonary epithelial–mesenchymal transition

As the primary cause of lung cancer, tobacco smoke (TS) promotes the initiation and progression of lung tumorigenesis. Epithelial-mesenchymal transition (EMT) is a crucial process involved in cell malignant transformation. The role of ERK5, the lesser studied member of MAPKs family, in regulating TS...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Liang, Zhaofeng, Xie, Wei, Wu, Rui, Geng, Hao, Zhao, Li, Xie, Chunfeng, Li, Xiaoting, Huang, Cong, Zhu, Jianyun, Zhu, Mingming, Zhu, Weiwei, Wu, Jieshu, Geng, Shanshan, Zhong, Caiyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637308/
https://ncbi.nlm.nih.gov/pubmed/25965818
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