Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder

Inflammation, which may be present in a subgroup of individuals with major depressive disorder (MDD), activates the kynurenine metabolic pathway to produce kynurenine metabolites kynurenic acid (KynA) and quinolinic acid (QA). We have previously reported an association between the ratio of KynA to Q...

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Veröffentlicht in:Psychoneuroendocrinology
Hauptverfasser: Savitz, Jonathan, Dantzer, Robert, Meier, Timothy B., Wurfel, Brent E., Victor, Teresa A., McIntosh, Scott A., Ford, Bart N., Morris, Harvey M., Bodurka, Jerzy, Teague, T. Kent, Drevets, Wayne C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637239/
https://ncbi.nlm.nih.gov/pubmed/26232650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2015.07.609
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