Putative Neuroprotective and Neurotoxic Kynurenine Pathway Metabolites Are Associated with Hippocampal and Amygdalar Volumes in Subjects with Major Depressive Disorder

Inflammation-related changes in the concentrations of kynurenine pathway metabolites occur in depression secondary to medical conditions but are not firmly established in primary mood disorders. Reductions in hippocampal and amygdalar volume that putatively reflect dendritic atrophy are widely repor...

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Détails bibliographiques
Publié dans:Neuropsychopharmacology
Auteurs principaux: Savitz, Jonathan, Drevets, Wayne C, Smith, Chelsey M, Victor, Teresa A, Wurfel, Brent E, Bellgowan, Patrick SF, Bodurka, Jerzy, Teague, T Kent, Dantzer, Robert
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443961/
https://ncbi.nlm.nih.gov/pubmed/25074636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.194
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