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Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification

A key event in the generation of a cellular response against malicious organisms through the endocytic pathway is binding of peptidic antigens by major histocompatibility complex class II (MHC class II) molecules. The bound peptide is then presented on the cell surface where it can be recognized by...

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Bibliographische Detailangaben
Veröffentlicht in:Immunogenetics
Hauptverfasser: Andreatta, Massimo, Karosiene, Edita, Rasmussen, Michael, Stryhn, Anette, Buus, Søren, Nielsen, Morten
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637192/
https://ncbi.nlm.nih.gov/pubmed/26416257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-015-0873-y
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