Uncovering the Peptide-Binding Specificities of HLA-C: A General Strategy To Determine the Specificity of Any MHC Class I Molecule

MHC class I molecules (HLA-I in humans) present peptides derived from endogenous proteins to CTLs. Whereas the peptide-binding specificities of HLA-A and -B molecules have been studied extensively, little is known about HLA-C specificities. Combining a positional scanning combinatorial peptide libra...

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Publicado en:J Immunol
Autores principales: Rasmussen, Michael, Harndahl, Mikkel, Stryhn, Anette, Boucherma, Rachid, Nielsen, Lise Lotte, Lemonnier, François A., Nielsen, Morten, Buus, Søren
Formato: Artigo
Lenguaje:Inglês
Publicado: AAI 2014
Materias:
Antigen Recognition and Responses
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226424/
https://ncbi.nlm.nih.gov/pubmed/25311805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401689
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