DNA methylation subgroups in melanoma are associated with proliferative and immunological processes

BACKGROUND: DNA methylation at CpG dinucleotides is modified in tumorigenesis with potential impact on transcriptional activity. METHODS: We used the Illumina 450 K platform to evaluate DNA methylation patterns of 50 metastatic melanoma tumors, with matched gene expression data. RESULTS: We identifi...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Med Genomics
Auteurs principaux: Lauss, Martin, Ringnér, Markus, Karlsson, Anna, Harbst, Katja, Busch, Christian, Geisler, Jürgen, Lønning, Per Eystein, Staaf, Johan, Jönsson, Göran
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636848/
https://ncbi.nlm.nih.gov/pubmed/26545983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0147-4
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