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Genome-wide miR-155 and miR-802 target gene identification in the hippocampus of Ts65Dn Down syndrome mouse model by miRNA sponges

BACKGROUND: Down syndrome (DS) or trisomy 21 is the result of a genetic dosage imbalance that translates in a broad clinical spectrum. A major challenge in the study of DS is the identification of functional genetic elements with wide impact on phenotypic alterations. Recently, miRNAs have been reco...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Bofill-De Ros, Xavier, Santos, Mónica, Vila-Casadesús, Maria, Villanueva, Eneko, Andreu, Nuria, Dierssen, Mara, Fillat, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636806/
https://ncbi.nlm.nih.gov/pubmed/26546125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2160-6
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