Protective effect of TSLP delivered at the gut mucosa level by recombinant lactic acid bacteria in DSS-induced colitis mouse model

BACKGROUND: Thymic stromal lymphopoietin (TSLP) is a cytokine known to mature dendritics cells, lower pro-inflammatory IL-12 secretion, induce differentiation of anti-inflammatory FoxP3+ regulatory T cells (Treg). Moreover, Crohn’s disease patients have shown a reduction of intestinal TSLP expressio...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Aubry, Camille, Michon, Christophe, Chain, Florian, Chvatchenko, Yolande, Goffin, Laurence, Zimmerli, Simone C., Leguin, Sylvia, Langella, Philippe, Bermudez-Humaran, Luis, Chatel, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636794/
https://ncbi.nlm.nih.gov/pubmed/26546058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0367-5
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