Serine protease inhibitors protect better than IL-10 and TGF-β anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci

BACKGROUND: Different studies have described the successful use of recombinant lactic acid bacteria (recLAB) to deliver anti-inflammatory molecules at the mucosal level to treat Inflammatory Bowel Disease (IBD). METHODS: In order to identify the best strategy to treat IBD using recLAB, we compared t...

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Bermúdez-Humarán, Luis G, Motta, Jean-Paul, Aubry, Camille, Kharrat, Pascale, Rous-Martin, Laurence, Sallenave, Jean-Michel, Deraison, Céline, Vergnolle, Nathalie, Langella, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371826/
https://ncbi.nlm.nih.gov/pubmed/25889561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0198-4
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