MHC Class I Expression by Donor Hematopoietic Stem Cells Is Required to Prevent NK Cell Attack in Allogeneic, but Not Syngeneic Recipient Mice

NK cells resist engraftment of syngeneic and allogeneic bone marrow (BM) cells lacking major histocompatibility (MHC) class I molecules, suggesting a critical role for donor MHC class I molecules in preventing NK cell attack against donor hematopoietic stem and progenitor cells (HSPCs), and their de...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Hirata, Yuichi, Li, Hao-Wei, Takahashi, Kazuko, Ishii, Hiroshi, Sykes, Megan, Fujisaki, Joji
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636372/
https://ncbi.nlm.nih.gov/pubmed/26544200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141785
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