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MHC Class I Expression by Donor Hematopoietic Stem Cells Is Required to Prevent NK Cell Attack in Allogeneic, but Not Syngeneic Recipient Mice

NK cells resist engraftment of syngeneic and allogeneic bone marrow (BM) cells lacking major histocompatibility (MHC) class I molecules, suggesting a critical role for donor MHC class I molecules in preventing NK cell attack against donor hematopoietic stem and progenitor cells (HSPCs), and their de...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Hirata, Yuichi, Li, Hao-Wei, Takahashi, Kazuko, Ishii, Hiroshi, Sykes, Megan, Fujisaki, Joji
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636372/
https://ncbi.nlm.nih.gov/pubmed/26544200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141785
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