Increased frequency of ICOS(+) CD4 T-cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy

Pharmacodynamic biomarkers can play an important role in understanding whether a therapeutic agent has “hit its target” to impact biologic function. A pharmacodynamic biomarker for anti-CTLA-4 therapy remains to be elucidated. We previously reported that anti-CTLA-4 therapy increases the frequency o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer Immunol Res
Hauptverfasser: Tang, Derek Ng, Shen, Yu, Sun, Jingjing, Wen, Sijin, Wolchok, Jedd D., Yuan, Jianda, Allison, James P., Sharma, Padmanee
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636341/
https://ncbi.nlm.nih.gov/pubmed/24777852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0020
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge