SOST Inhibits Prostate Cancer Invasion

Inhibitors of Wnt signaling have been shown to be involved in prostate cancer (PC) metastasis; however the role of Sclerostin (Sost) has not yet been explored. Here we show that elevated Wnt signaling derived from Sost deficient osteoblasts promotes PC invasion, while rhSOST has an inhibitory effect...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Hudson, Bryan D., Hum, Nicholas R., Thomas, Cynthia B., Kohlgruber, Ayano, Sebastian, Aimy, Collette, Nicole M., Coleman, Matthew A., Christiansen, Blaine A., Loots, Gabriela G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636315/
https://ncbi.nlm.nih.gov/pubmed/26545120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142058
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