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Deciphering Transcriptional Dynamics In Vivo by Counting Nascent RNA Molecules

Deciphering how the regulatory DNA sequence of a gene dictates its expression in response to intra and extracellular cues is one of the leading challenges in modern genomics. The development of novel single-cell sequencing and imaging techniques, as well as a better exploitation of currently availab...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Choubey, Sandeep, Kondev, Jane, Sanchez, Alvaro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636183/
https://ncbi.nlm.nih.gov/pubmed/26544860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004345
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