Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus

Cancer immunotherapy has been revolutionised by the use monoclonal antibodies (mAb) that function through their interaction with Fc gamma receptors (FcγRs). The low-affinity FcγR genes are highly homologous, map to a complex locus at 1p23 and harbour single nucleotide polymorphisms (SNPs) and copy n...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Hargreaves, Chantal E., Iriyama, Chisako, Rose-Zerilli, Matthew J. J., Nagelkerke, Sietse Q., Hussain, Khiyam, Ganderton, Rosalind, Lee, Charlotte, Machado, Lee R., Hollox, Edward J., Parker, Helen, Latham, Kate V., Kuijpers, Taco W., Potter, Kathleen N., Coupland, Sarah E., Davies, Andrew, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R., Glennie, Martin J., Cragg, Mark S., Strefford, Jonathan C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636148/
https://ncbi.nlm.nih.gov/pubmed/26545243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142379
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