Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus

Cancer immunotherapy has been revolutionised by the use monoclonal antibodies (mAb) that function through their interaction with Fc gamma receptors (FcγRs). The low-affinity FcγR genes are highly homologous, map to a complex locus at 1p23 and harbour single nucleotide polymorphisms (SNPs) and copy n...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Hargreaves, Chantal E., Iriyama, Chisako, Rose-Zerilli, Matthew J. J., Nagelkerke, Sietse Q., Hussain, Khiyam, Ganderton, Rosalind, Lee, Charlotte, Machado, Lee R., Hollox, Edward J., Parker, Helen, Latham, Kate V., Kuijpers, Taco W., Potter, Kathleen N., Coupland, Sarah E., Davies, Andrew, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R., Glennie, Martin J., Cragg, Mark S., Strefford, Jonathan C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636148/
https://ncbi.nlm.nih.gov/pubmed/26545243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142379
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