Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus

Cancer immunotherapy has been revolutionised by the use monoclonal antibodies (mAb) that function through their interaction with Fc gamma receptors (FcγRs). The low-affinity FcγR genes are highly homologous, map to a complex locus at 1p23 and harbour single nucleotide polymorphisms (SNPs) and copy n...

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Publicado no:PLoS One
Main Authors: Hargreaves, Chantal E., Iriyama, Chisako, Rose-Zerilli, Matthew J. J., Nagelkerke, Sietse Q., Hussain, Khiyam, Ganderton, Rosalind, Lee, Charlotte, Machado, Lee R., Hollox, Edward J., Parker, Helen, Latham, Kate V., Kuijpers, Taco W., Potter, Kathleen N., Coupland, Sarah E., Davies, Andrew, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R., Glennie, Martin J., Cragg, Mark S., Strefford, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636148/
https://ncbi.nlm.nih.gov/pubmed/26545243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142379
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