Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing

Ubiquitination of the replication clamp proliferating cell nuclear antigen (PCNA) at the conserved residue lysine (K)164 triggers postreplicative repair (PRR) to fill single-stranded gaps that result from stalled DNA polymerases. However, it has remained elusive as to whether cells engage PRR in res...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Becker, Jordan R., Pons, Carles, Nguyen, Hai Dang, Costanzo, Michael, Boone, Charles, Myers, Chad L., Bielinsky, Anja-Katrin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636136/
https://ncbi.nlm.nih.gov/pubmed/26545110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005659
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