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Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1
The transferrin receptor 1 (TfR1) is involved in cellular iron uptake and regulation of cell proliferation. The increased expression of TfR1 observed in malignant cells, compared to normal cells, together with its extracellular accessibility, make this receptor an attractive target for antibody-medi...
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| Publicado no: | Mol Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636009/ https://ncbi.nlm.nih.gov/pubmed/26232328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2015.07.001 |
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