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Obesity promotes colonic stem cell expansion during cancer initiation
There is an urgent need to elucidate the mechanistic links between obesity and colon cancer. Convincing evidence for the role of Lgr5(+)stem cells in colon tumorigenesis has been established, however, the influence of obesity on stem cell maintenance is unknown. We assessed the effects of high fat (...
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| Publicado no: | Cancer Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636003/ https://ncbi.nlm.nih.gov/pubmed/26455770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.10.001 |
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