Virtual High-Throughput Screening To Identify Novel Activin Antagonists

Activin belongs to the TGFβ superfamily, which is associated with several disease conditions, including cancer-related cachexia, preterm labor with delivery, and osteoporosis. Targeting activin and its related signaling pathways holds promise as a therapeutic approach to these diseases. A small-mole...

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Bibliographic Details
Published in:J Med Chem
Main Authors: Zhu, Jie, Mishra, Rama K., Schiltz, Gary E., Makanji, Yogeshwar, Scheidt, Karl A., Mazar, Andrew P., Woodruff, Teresa K.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635973/
https://ncbi.nlm.nih.gov/pubmed/26098096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00753
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