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Tim-3 and Tim-4 as the potential targets for antitumor therapy
Both Tim-3 and Tim-4 belong to the T-cell immunoglobulin and mucin domain (Tim) gene family, which plays a critical role in immunoregulation. Tim-3 has been suggested as a negative regulator of anti-tumor immunity due to its function on inducing T cells exhaustion in cancer. In addition to its expre...
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| Veröffentlicht in: | Hum Vaccin Immunother |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4635934/ https://ncbi.nlm.nih.gov/pubmed/26211834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1056953 |
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