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Tim-3 and Tim-4 as the potential targets for antitumor therapy

Both Tim-3 and Tim-4 belong to the T-cell immunoglobulin and mucin domain (Tim) gene family, which plays a critical role in immunoregulation. Tim-3 has been suggested as a negative regulator of anti-tumor immunity due to its function on inducing T cells exhaustion in cancer. In addition to its expre...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Cheng, Lin, Ruan, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635934/
https://ncbi.nlm.nih.gov/pubmed/26211834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1056953
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