Association of Extrarenal Adverse Effects of Posttransplant Immunosuppression With Sex and ABCB1 Haplotypes

Extrarenal adverse effects (AEs) associated with calcineurin inhibitor (CNI) and mycophenolic acid (MPA) occur frequently but are unpredictable posttransplant complications. AEs may result from intracellular CNI accumulation and low activity of P-glycoprotein, encoded by the ABCB1 gene. Since ABCB1...

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Publicat a:Medicine (Baltimore)
Autors principals: Venuto, Rocco C., Meaney, Calvin J., Chang, Shirley, Leca, Nicolae, Consiglio, Joseph D., Wilding, Gregory E., Brazeau, Daniel, Gundroo, Aijaz, Nainani, Neha, Morse, Sarah E., Cooper, Louise M., Tornatore, Kathleen M.
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Health 2015
Matèries:
5200
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635790/
https://ncbi.nlm.nih.gov/pubmed/26376376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000001315
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