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Complexation Hydrogels as Oral Delivery Vehicles of Therapeutic Antibodies: An in Vitro and ex Vivo Evaluation of Antibody Stability and Bioactivity

Oral administration of monoclonal antibodies (mAbs) may enable the localized treatment of infections or other conditions in the gastrointestinal tract (GI) as well as systemic diseases. As with the development of oral protein biotherapeutics, one of the most challenging tasks in antibody therapies i...

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Detalhes bibliográficos
Publicado no:Ind Eng Chem Res
Main Authors: Carrillo-Conde, Brenda R., Brewer, Erik, Lowman, Anthony, Peppas, Nicholas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635685/
https://ncbi.nlm.nih.gov/pubmed/26556950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.iecr.5b01193
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