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Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity

Cyclooxygenase-2 (COX-2), an inducible form of the enzyme that catalyzes the first step in the synthesis of prostanoids, is associated with inflammatory diseases and carcinogenesis, which is suspected to promote angiogenesis and tissue invasion of tumors and resistance to apoptosis. Meanwhile, COX-2...

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Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Liu, Bing, Qu, Liyan, Yan, Shigui
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635545/
https://ncbi.nlm.nih.gov/pubmed/26549987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0260-7
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