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Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia

Genetic evidence has supported the hypothesis that schizophrenia (SZ) is a polygenic disorder caused by the disruption in function of several or many genes. The most common and reproducible cellular phenotype associated with SZ is a reduction in dendritic spines within the neocortex, suggesting alte...

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Détails bibliographiques
Publié dans:Mol Neuropsychiatry
Auteurs principaux: Hjelm, Brooke E., Rollins, Brandi, Mamdani, Firoza, Lauterborn, Julie C., Kirov, George, Lynch, Gary, Gall, Christine M., Sequeira, Adolfo, Vawter, Marquis P.
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635522/
https://ncbi.nlm.nih.gov/pubmed/26550561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000441252
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