Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence

Subjects with schizophrenia (SZ) and bipolar disorder (BD) show decreased protein and transcript levels for mitochondrial complex I. In vitro results suggest antipsychotic and antidepressant drugs may be responsible. We measured complex I activity in BD, SZ, and controls and presence of antipsychoti...

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Detalhes bibliográficos
Publicado no:Mol Neuropsychiatry
Main Authors: Rollins, Brandi L., Morgan, Ling, Hjelm, Brooke E., Sequeira, Adolfo, Schatzberg, Alan F., Barchas, Jack D., Lee, Francis S., Myers, Rick M., Watson, Stanley J., Akil, Huda, Potkin, Steven G., Bunney, William E., Vawter, Marquis P.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2018
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836256/
https://ncbi.nlm.nih.gov/pubmed/29594135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000484348
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