Recombinase-based conditional and reversible gene regulation via XTR alleles

Synthetic biological tools that enable precise regulation of gene function within in vivo systems have enormous potential to discern gene function in diverse physiological settings. Here we report the development and characterization of a synthetic gene switch that, when targeted in the mouse germli...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Robles-Oteiza, Camila, Taylor, Sarah, Yates, Travis, Cicchini, Michelle, Lauderback, Brian, Cashman, Christopher R., Burds, Aurora A., Winslow, Monte M., Jacks, Tyler, Feldser, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635517/
https://ncbi.nlm.nih.gov/pubmed/26537451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9783
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